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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN6
All Species:
24.55
Human Site:
T459
Identified Species:
41.54
UniProt:
P51797
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51797
NP_001277.1
869
97217
T459
Q
L
F
H
Q
D
G
T
F
S
P
V
T
L
A
Chimpanzee
Pan troglodytes
XP_514393
802
89426
L408
F
F
V
L
Y
F
L
L
A
C
W
T
Y
G
I
Rhesus Macaque
Macaca mulatta
XP_001104721
869
97094
T459
Q
L
F
H
Q
D
G
T
F
S
P
V
T
L
A
Dog
Lupus familis
XP_535404
889
99260
T479
Q
L
F
H
Q
D
G
T
F
S
P
V
T
L
A
Cat
Felis silvestris
Mouse
Mus musculus
O35454
870
96962
T460
Q
L
F
H
Q
D
G
T
F
S
P
V
T
L
A
Rat
Rattus norvegicus
P51799
803
88712
C409
I
R
Y
I
H
R
P
C
L
Q
V
I
E
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516296
878
97865
H471
P
S
G
N
G
S
F
H
P
Q
N
P
S
E
D
Chicken
Gallus gallus
XP_417644
868
97172
T458
Q
L
F
H
Q
D
G
T
F
S
P
V
T
L
S
Frog
Xenopus laevis
Q9W701
689
76782
L295
I
L
G
V
V
C
G
L
I
G
C
A
Y
L
F
Zebra Danio
Brachydanio rerio
XP_696527
863
96883
T454
Q
L
F
H
Q
N
A
T
F
S
P
V
T
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
A409
K
W
L
K
V
I
E
A
L
I
V
A
A
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193438
761
83935
T367
G
Y
Y
N
D
M
A
T
L
F
F
N
P
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
C398
V
P
D
S
G
I
E
C
P
R
P
P
G
M
Y
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
T385
Q
E
V
L
F
L
A
T
L
T
A
L
I
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
99.4
93.3
N.A.
96.7
40.8
N.A.
81.3
93.2
22.7
82.6
N.A.
N.A.
37.9
N.A.
49.8
Protein Similarity:
100
92.2
99.8
95.1
N.A.
98.7
58
N.A.
85.3
97.8
39.1
90.7
N.A.
N.A.
57.3
N.A.
64.6
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
0
93.3
20
80
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
0
100
100
N.A.
100
13.3
N.A.
13.3
100
20
93.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
30
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
22
8
8
0
8
15
8
8
29
% A
% Cys:
0
0
0
0
0
8
0
15
0
8
8
0
0
0
0
% C
% Asp:
0
0
8
0
8
36
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
8
0
0
0
0
15
0
0
0
0
0
8
8
8
% E
% Phe:
8
8
43
0
8
8
8
0
43
8
8
0
0
0
8
% F
% Gly:
8
0
15
0
15
0
43
0
0
8
0
0
8
8
0
% G
% His:
0
0
0
43
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
8
0
15
0
0
8
8
0
8
8
0
8
% I
% Lys:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
50
8
15
0
8
8
15
29
0
0
8
0
58
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
15
0
8
0
0
0
0
8
8
0
0
0
% N
% Pro:
8
8
0
0
0
0
8
0
15
0
50
15
8
0
0
% P
% Gln:
50
0
0
0
43
0
0
0
0
15
0
0
0
8
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
8
0
8
0
8
0
0
0
43
0
0
8
8
22
% S
% Thr:
0
0
0
0
0
0
0
58
0
8
0
8
43
0
0
% T
% Val:
8
0
15
8
15
0
0
0
0
0
15
43
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
15
0
8
0
0
0
0
0
0
0
15
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _